Vax-CT to promote formation of cancer-specific T memory stem cell for personalized cancer immunotherapy

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Research Objective A vaccine booster to induce antigen-specific T memory stem cells that will help enhance the long-term immunity against cancer recurrence Impact Cancer recurrence presents an unmet medical need.…

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Modulation of oral epithelium stem cells by RSpo1 for the prevention and treatment of oral mucositis

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Research Objective Locally delivered formulation of RSpo1 protein as an activator of Lgr5+ epithelial stem cells in chemotherapy- or radiation therapy-induced oral mucositis Impact Oral mucositis Major Proposed Activities RSpo1…

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iPSC-derived smooth muscle cell progenitor conditioned medium for treatment of pelvic organ prolapse

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Research Objective Conditioned media from human iPSC-derived smooth muscle cell progenitors. This media exerts paracrine effect to restore damaged vaginal wall in patients with pelvic organ prolapse. Impact Pelvic organ…

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