Video Topic: Spotlights on Disease


Spotlight on Amyloidosis and Stem Cell Research: Robert Vescio MD – Cedars-Sinai

Dr. Robert Vescio spoke to CIRM’s governing board to promote awareness about amyloidosis, a rare, often fatal disease caused by the abnormal deposit of proteins called amyloids in various tissues of the body. Dr. Vescio, director of Cedars-Sinai’s multiple myeloma and amyloidosis program, explained the disease and described the current stem cell based treatment options. […]

Michael York: Amyloidosis and Stem Cell Research

Michael York, star of films such as Cabaret, Logan’s Run, and Austin Powers, spoke to the California stem cell agency governing board about his personal battle with amyloidosis, a rare, often fatal disease caused by the abnormal deposit of proteins called amyloids in various tissues of the body. In addition to amyloidosis, York was also […]

Spotlight on Muscular Dystrophy and Stem Cell Research – Helen Blau, Stanford

Duchenne muscular dystrophy (DMD) is the most severe form of muscular dystrophy that affects 1 in 3500 boys and leads to progressive muscle degeneration and death by the second decade of life. It’s been nearly thirty years ago that dystrophin, the mutated gene that causes DMD, was identified. Without the large structural protein encoded by […]

HIV/AIDS Stem Cell Clinical Trial: Introduction by Jeff Sheehy

On July 9th 2013, Calimmune announced they had treated the first patient in a clinical trial involving the use of an innovative gene-based stem cell therapy to help protect individuals infected with HIV from the effects of the AIDS virus. Jeff Sheehy, the HIV/AIDS patient advocate board member for California’s Stem Cell Agency (CIRM), describes […]

HIV/AIDS Stem Cell Clinical Trial: Louis Breton, CEO, Calimmune

On July 9th 2013, Calimmune announced they had treated the first patient in a clinical trial involving the use of an innovative gene-based stem cell therapy to help protect individuals infected with HIV from the effects of the AIDS virus. Calimmune CEO Louis Breton spoke to the governing board of California’s Stem Cell Agency (CIRM) […]

HIV/AIDS Stem Cell Clinical Trial: Geoff Symonds, Calimmune

On July 9th 2013, Calimmune announced they had treated the first patient in a clinical trial involving the use of an innovative gene-based stem cell therapy to help protect individuals infected with HIV from the effects of the AIDS virus. Calimmune Chief Scientific Office, Geoff Symonds, PhD detailed the clinical trial procedure to the governing […]

Spotlight on Stem Cell Advances in Pediatric Heart Disease: A Change of Heart

One percent of live births have heart defects, the leading noninfectious cause of death in the 1st year. Using embryonic stem cell technology, Dr. Deepak Srivastava’s lab has made many insights into understand the genetic networks that control heart development as well the genetic mutations that are involved in heart defects. With these findings in […]

Spotlight on Stem Cell Advances in Heart Disease: Generating Muscle within an Existing Heart

Long-term stem cell-based strategies for heart disease aim to rebuild parts of the heart. But investigators like Deepak Srivastava are also looking into more near term goals to regenerate heart muscle from within the existing heart through direct reprogramming. Dr. Srivastava spoke about his recent work in this area to the CIRM Governing Board during […]

Joshua’s Heart Story: Pediatric Heart Disease and the Promise of Stem Cell Advances

The day before 9/11,  just four months pregnant, Mary Goulart and her husband learned through ultrasounds that their baby had several heart defects including a missing left ventricle. After birth, baby Joshua endured three open-heart surgeries and a massive stroke. Through years of various therapies and true determination, Joshua met his challenges with many accomplishments.  […]

Advancing Toward Multiple Sclerosis Therapies Using Stem Cells

Dr. Tom Lane of the University of Utah (formerly a CIRM grantee at UC-Irvine) describes his lab’s experimental results that show a dramatic reversal in the debilitating effects of a multiple sclerosis (MS)-like illness in mice after treating them with human neural stem cells. After just two weeks, the mice—who had previously been unable to […]