Download Unit 1

Unit 1: Embryonic Stem Cells, Natural and In Vitro Fertilization, Preimplantation Genetic Diagnosis

By Kathy Keeran, Lonnie Simonson, and Laurel Barchas
 

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Suggested time frame: One to six class periods

Course level: Beginning Biology, review for AP biology, community college beginning biology classes

Inquiry teaching: Read how to modify the curriculum for inquiry teaching

 

 

Brief outline of Unit 1 with download links

I. Invitation and pre-assessment

1. Writing activity
2. My Sister’s Keeper, Octomom

II. Exploration

A. Natural fertilization and development of embryonic stem cell lines; origins of totipotent and pluripotent stem cells

1. Lecture with power point- stages of embryonic and fetal development

i. Download Appendix A: Natural Fertilization presentation [power point]
ii. Download Appendix A: Unit One Natural Fertilization student worksheet [pdf]
iii. Download Appendix A: Unit One Natural Fertilization teacher version [pdf]

2. Animation of natural fertilization

3. Lab- sea urchin development

i. Download Appendix B: sea urchin microscope labgraphic organizer [pdf]

4. Embryonic development and location of stages and sites at which totipotent and pluripotent stem cells occur.

i. Download Appendix C: Playdough-modeling Activity [pdf]

B. In Vitro Fertilization and what happens to un-implanted embryos

1. Video clips, animations and discussion of in vitro fertilization: Northern Calif. Fertility Medical Center, Howard Hughes Medical Institute

i. Download Appendix D: student graphic organizer [pdf]
ii. Download Appendix D:teacher answer sheet [pdf]

2. Animation of intra-cytoplasmic sperm injection- Schering-Plough production of ICSI procedure

C. Pre-implantation genetic diagnosis (PGD) techniques, uses and ethical considerations

1. Animation and discussion of stem cell lines and ability of stem cells to differentiate; medical uses
2. Jigsaw study of scientific paper summaries; includes jigsaw instructions

i. Download Appendix E: jigsaw general instructions [pdf]
ii. Download Appendix E: Summaries of research papers [pdf]

III. Application

1. Discussion of ethics of PGD following jigsaw
2. Ranking exercise of policy options with graphic organizer

i. Download Appendix F: policy options ranking sheet [pdf]

IV. Assessment

1. Post- assessment thought questions

i. Download Appendix G: Unit Assessment [pdf]

 

 

 

 

 

 

 

© 2013 California Institute for Regenerative Medicine