Active Awards Portfolio Dashboard
It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.
| Disease | Cell Type | Therapeutic or Technology | Institution | Stage | Project Objective | Details |
|---|---|---|---|---|---|---|
| Age-related macular degeneration, Retinitis Pigmentosa, Vision Loss | Directly Reprogrammed Cell | Donor cell therapy, Specific Cell Type Derivation, Technology, Therapeutic Approach | CHLA |  |
Development Candidate, Proof of Concept | |
| Brain Cancer, Cancer, Solid Tumors | Cancer Stem Cell | Biologic, Gene modification, Therapeutic Approach | UC Irvine | |
Development Candidate, Proof of Concept | |
| Amyotrophic Lateral Sclerosis, Neurological Disorders | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCSF | |
Development Candidate | |
| HIV/AIDS, Infectious Disease | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCLA | |
Development Candidate | ||
| Neurological Disorders, Neuropathy | iPS Cell | Small molecule therapy, Therapeutic Approach | UCSF | |
Development Candidate | |
| Brain Cancer, Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | COH | |
Development Candidate | |
| Heart Disease, Heart failure | Embryonic Stem Cell, iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCSD | |
Development Candidate | |
| Diabetes, Metabolic Disorders, Type 1 diabetes | Adult or Tissue Stem Cell | Antibody, Biologic, Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSF | |
Development Candidate | |
| Neurological Disorders, Traumatic Brain Injury | iPS Cell | Donor cell therapy, Therapeutic Approach | PAVIR | |
Development Candidate, Proof of Concept | |
| Neurological Disorders, Stroke | iPS Cell | Donor cell therapy, Therapeutic Approach | PAVIR | |
Development Candidate, Proof of Concept | |
| Neurological Disorders | iPS Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Savanna Bio | |
Development Candidate, Proof of Concept | |
| Amyotrophic Lateral Sclerosis, Neurological Disorders | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | USC | |
Development Candidate, Proof of Concept | |
| Intestinal Disease, Metabolic Disorders | iPS Cell | Small molecule therapy, Therapeutic Approach | UCSF | |
Development Candidate, Proof of Concept | |
| Amyotrophic Lateral Sclerosis, Neurological Disorders | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Cedars-Sinai | |
Development Candidate, Proof of Concept | |
| Neurological Disorders | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UC Davis | |
Development Candidate, Proof of Concept | |
| Vision Loss | Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Adverum Biotechnologies | |
Development Candidate, Proof of Concept | |
| Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML) | Somatic Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Immune tolerance/management, Technology, Therapeutic Approach | Stanford | |
Development Candidate | |
| Infectious Disease, Neurological Disorders | iPS Cell | Gene editing tools, Gene Therapy (All), Gene-modified, donor cell therapy, Immune tolerance/management, Technology, Therapeutic Approach | UCSF | |
Development Candidate, Proof of Concept | |
| Breast Cancer, Cancer, Solid Tumors | Cancer Stem Cell | Small molecule therapy, Therapeutic Approach | Stanford | |
Development Candidate | |
| Liver Disease, Metabolic Disorders | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | USC | |
Development Candidate, Proof of Concept | |
| Heart Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Cedars-Sinai | |
Development Candidate, Proof of Concept | |
| Cancer, Prostate Cancer, Solid Tumors | iPS Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | UC Irvine | |
Development Candidate, Proof of Concept | |
| Neurological Disorders, Spinal Cord Injury | Embryonic Stem Cell, iPS Cell | Donor cell therapy, Therapeutic Approach | Gladstone | |
Development Candidate, Proof of Concept | |
| Cancer, Melanoma, Solid Tumors | Adult or Tissue Stem Cell | Biologic, Small molecule therapy, Therapeutic Approach, Vaccine | UCLA | |
Proof of Concept | |
| Breast Cancer, Cancer, Solid Tumors | Adult or Tissue Stem Cell, Cancer Stem Cell | Small molecule therapy, Therapeutic Approach | UCLA | |
Development Candidate, Proof of Concept | |
| Duchenne Muscular Dystrophy, Genetic Disorder, Skeletal/Smooth Muscle disorders | iPS Cell | Model system development, Technology | Greenstone Biosciences | |
Tool/Resources/Bottleneck | |
| Blood Disorders, Severe Combined Immunodeficiency, Artemis deficient (ART-SCID) | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UC Berkeley | |
Development Candidate | |
| Duchenne Muscular Dystrophy, Skeletal/Smooth Muscle disorders | Other, Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UC Davis | |
Proof of Concept | |
| Lung Disease, Fibrosis, Respiratory Disorders | Adult or Tissue Stem Cell | Small molecule therapy, Therapeutic Approach | Rubedo Life Sciences Inc. | |
Development Candidate, Proof of Concept | |
| Autism, Intellectual Disability, Metabolic Disorders, Neurological Disorders | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCLA | |
Development Candidate, Proof of Concept | |
| Brain Cancer, Cancer, Solid Tumors | Cancer Stem Cell | Small molecule therapy, Therapeutic Approach | UCLA | |
Development Candidate | |
| Bone or Cartilage Disease, Tendon/Ligament/Connective Tissue Injury or Disorder | Embryonic Stem Cell | Donor cell therapy, Other Components, Therapeutic Approach | Scripps Health | |
Development Candidate, Proof of Concept | |
| Bone or Cartilage Disease, Intervertebral disc degeneration | iPS Cell | Donor cell therapy, Other Components, Therapeutic Approach | Cedars-Sinai | |
Development Candidate, Proof of Concept | |
| Metabolic Disorders, Neurological Disorders, Sanfilippo Syndrome/MPS III | Embryonic Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | Lundquist Institute | |
Development Candidate, Proof of Concept | |
| Heart Disease, Heart failure | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UC Berkeley | |
Development Candidate, Proof of Concept | |
| Neurological Disorders, Spinal Cord Injury | Embryonic Stem Cell, iPS Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | BrainXell Therapeutics | |
Development Candidate, Proof of Concept | |
| Heart Disease, Heart failure | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Gladstone | |
Development Candidate, Proof of Concept | |
| HIV/AIDS, Infectious Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Scintillon Inst | |
Development Candidate, Proof of Concept | |
| Cancer, Solid Tumors | Somatic Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UC Irvine | |
Development Candidate | |
| iPS Cell | Model system development, Specific Cell Type Derivation, Technology | Nanotools Bioscience | |
Proof of Concept | ||
| Vision Loss | Embryonic Stem Cell, iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCLA | |
Development Candidate, Proof of Concept | |
| Autism, Epilepsy, Neurological Disorders, Other | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | UCSD | |
Development Candidate, Proof of Concept | |
| Intestinal Disease, Metabolic Disorders | iPS Cell | Exploring disease mechanisms, Model system development, Technology | Cedars-Sinai | |
Proof of Concept, Tool/Resources/Bottleneck | |
| Epilepsy, Neurological Disorders, Other | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UC Davis | |
Development Candidate, Proof of Concept | |
| Blood Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Development Candidate, Proof of Concept | |
| Alpha Thalassemia Major, Blood Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Development Candidate | |
| Cancer, Other, Skin Disease, Wounds, ulcers | Adult or Tissue Stem Cell | Biologic, Protein/peptide therapy, Therapeutic Approach | Intact Therapeutics, Inc. | |
Development Candidate, Proof of Concept | |
| Cancer, Sarcoma, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | |
Development Candidate, Proof of Concept | |
| Heart Disease | iPS Cell | Model system development, Specific Cell Type Derivation, Technology | Stanford | |
Development Candidate, Proof of Concept | |
| Epidermolysis Bullosa, Skin Disease | iPS Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | |
Development Candidate, Proof of Concept |
