Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

Disease	Cell Type	Therapeutic or Technology	Institution	Stage	Project Objective	Details
Neurological Disorders	iPS Cell	Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach	Navega Therapeutics		Development Candidate, Proof of Concept
Heart Disease	iPS Cell	Model system development, Specific Cell Type Derivation, Technology	Stanford		Development Candidate, Proof of Concept
Amyotrophic Lateral Sclerosis, Neurological Disorders	Adult or Tissue Stem Cell	Donor cell therapy, Small molecule therapy, Therapeutic Approach	UCSD		Development Candidate, Proof of Concept
Epidermolysis Bullosa, Skin Disease	iPS Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	Stanford		Development Candidate, Proof of Concept
Heart Disease, Heart failure	Embryonic Stem Cell, iPS Cell	Biologic, Exosomes based therapy, Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach	Stanford		Development Candidate, Proof of Concept
Heart Disease	iPS Cell	Donor cell therapy, Therapeutic Approach	UC Davis		Development Candidate, Proof of Concept
Liver Disease, Metabolic Disorders	iPS Cell	Donor cell therapy, Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach	CHLA		Development Candidate, Proof of Concept
Cancer, Solid Tumors	Adult or Tissue Stem Cell	Technology	Stanford		Tool/Resources/Bottleneck
	iPS Cell	Cell processing & handling, Technology	Defined Bioscience, Inc.		Tool/Resources/Bottleneck
	iPS Cell	Cell Line Generation-Resource, Gene Therapy (All), Gene-modified, donor cell therapy, Immune tolerance/management, Technology, Therapeutic Approach	HEALIOS NA, Inc.		Tool/Resources/Bottleneck
aa Multiple Diseases (Centers & Resoures)		Cell processing & handling, Technology	UC Davis		Tool/Resources/Bottleneck
Other, Toxicity	iPS Cell	Model system development, Technology	Greenstone Biosciences		Tool/Resources/Bottleneck
Heart Disease	iPS Cell	Model system development, Technology	Organos, Inc.		Tool/Resources/Bottleneck
Kidney Disease, Kidney Failure	Adult or Tissue Stem Cell	Device, Technology, Therapeutic Approach, Tissue engineering	UC Davis		Pre-IND/IDE or Equivalent
Breast Cancer, Cancer, Solid Tumors	Cancer Stem Cell	Assay development, Diagnostic Test, Technology	Cedars-Sinai		Regulated Lab Test, Ready for Validation
Epilepsy, Neurological Disorders	Embryonic Stem Cell	Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach	Neurona Therapeutics		Pre-IND/IDE or Equivalent
Cancer, Ovarian Cancer, Solid Tumors	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach	UCLA		Pre-IND/IDE or Equivalent
Blood Disorders, Bone or Cartilage Disease, Metabolic Disorders	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	Stanford		Pre-IND/IDE or Equivalent
Amyotrophic Lateral Sclerosis, Neurological Disorders		Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach	AcuraStem Incorporated		Pre-IND/IDE or Equivalent
Neurological Disorders, Parkinson's Disease	Embryonic Stem Cell	Cell processing & handling, Donor cell therapy, Technology, Therapeutic Approach	Axent Biosciences Inc.		Pre-IND/IDE or Equivalent
Metabolic Disorders		Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach	UCLA		Pre-IND/IDE or Equivalent
Age-related macular degeneration, Vision Loss	Somatic Cell	Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach	Ray Therapeutics, INC		Pre-IND/IDE or Equivalent
Other	Adult or Tissue Stem Cell	Small molecule therapy, Therapeutic Approach	UCSF		Pre-IND/IDE or Equivalent
Brain Cancer, Cancer, Solid Tumors	Somatic Cell	Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach	Siren Biotechnology, Inc.		Pre-IND/IDE or Equivalent
Bone or Cartilage Disease, Immune Disease, Skin Disease, Tendon/Ligament/Connective Tissue Injury or Disorder		Biologic, Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach	Cedars-Sinai		Pre-IND/IDE or Equivalent
Heart Disease	Adult or Tissue Stem Cell	Biologic, Therapeutic Approach	UCSD		Pre-IND/IDE or Equivalent
Blood Disorders	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCLA		Pre-IND/IDE or Equivalent
Blood Disorders, Genetic Disorder	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCLA		Pre-IND/IDE or Equivalent
Danon Disease, Genetic Disorder, Metabolic Disorders	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCSD		Pre-IND/IDE or Equivalent
Metabolic Disorders		Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach	UCLA		Pre-IND/IDE or Equivalent
Blood Cancer, Cancer, Multiple Myeloma	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach	COH		Pre-IND/IDE or Equivalent
Corneal Damage, Vision Loss		Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach	UCLA		Pre-IND/IDE or Equivalent
Blood Disorders	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	ImmunoVec		Pre-IND/IDE or Equivalent
Neurological Disorders, Parkinson's Disease	iPS Cell	Personalized cell therapy, Therapeutic Approach	BrainXell Therapeutics		Pre-IND/IDE or Equivalent
Corneal Damage, Vision Loss	Adult or Tissue Stem Cell	Biologic, Exosomes based therapy, Therapeutic Approach	UCLA		Pre-IND/IDE or Equivalent
HIV/AIDS, Infectious Disease	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCLA		Pre-IND/IDE or Equivalent
Lung Disease, Fibrosis, Respiratory Disorders		Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach	Rejuvenation Technologies, Inc.		Pre-IND/IDE or Equivalent
Cancer, Lung Cancer, Solid Tumors	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	USC		Pre-IND/IDE or Equivalent
Diabetes, Metabolic Disorders		Personalized cell therapy, Therapeutic Approach	Stanford		Pre-IND/IDE or Equivalent
Infectious Disease		Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach	VxBiosciences inc.		Pre-IND/IDE or Equivalent
Breast Cancer, Cancer, Solid Tumors	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach	COH		Pre-IND/IDE or Equivalent
Neurological Disorders, Pediatrics		Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach	Mahzi Therapeutics		Pre-IND/IDE or Equivalent
B cell cancers, Blood Cancer, Cancer		Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UC Davis		Pre-IND/IDE or Equivalent
Genetic Disorder, Neurological Disorders, Other, Pediatrics	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCSD		Pre-IND/IDE or Equivalent
Cancer, Prostate Cancer, Solid Tumors		Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	USC		Pre-IND/IDE or Equivalent
Heart Disease, Hypertension, pulmonary arterial, Pulmonary Hypertension	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCLA		Pre-IND/IDE or Equivalent
Neurological Disorders, Spinal Cord Injury	Adult or Tissue Stem Cell	Donor cell therapy, Therapeutic Approach	UC Irvine		Pre-IND/IDE or Equivalent
B cell cancers, Blood Cancer, Cancer	Somatic Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCSF		Pre-IND/IDE or Equivalent
Duchenne Muscular Dystrophy, Skeletal/Smooth Muscle disorders	Somatic Cell	Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach	MyoGene Bio LLC		Pre-IND/IDE or Equivalent
Genetic Disorder, Metabolic Disorders	Somatic Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	Immusoft Corporation		Pre-IND/IDE or Equivalent