Active Awards Portfolio Dashboard
It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.
Disease | Cell Type | Therapeutic or Technology | Institution | Stage | Project Objective | Details |
---|---|---|---|---|---|---|
Heart Disease | iPS Cell | Biologic, Protein/peptide therapy, Therapeutic Approach | Regencor, Inc. | Pre-IND/IDE or Equivalent | ||
Blood Disorders, IPEX Syndrome | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | ImmunoVec | Pre-IND/IDE or Equivalent | ||
Heart Disease | Antibody, Biologic, Therapeutic Approach | UCLA | Pre-IND/IDE or Equivalent | |||
Neurological Disorders, Stroke | iPS Cell | Donor cell therapy, Therapeutic Approach | PAVIR | Pre-IND/IDE or Equivalent | ||
Cancer, Melanoma, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | Pre-IND/IDE or Equivalent | ||
Blood Cancer, Cancer, Multiple Myeloma | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | UCLA | Pre-IND/IDE or Equivalent | ||
Brain Injury, hypoxic, ischemic, Neurological Disorders, Pediatrics | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Sanford-Burnham | Pre-IND/IDE or Equivalent | ||
Blood Cancer, Cancer, Multiple Myeloma | Adult or Tissue Stem Cell | Personalized cell therapy, Therapeutic Approach | UCLA | Pre-IND/IDE or Equivalent | ||
Neurological Disorders, Traumatic Brain Injury | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | UC Irvine | Pre-IND/IDE or Equivalent | ||
Blood Disorders, Hyper IgM Syndrome, Immune Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | Pre-IND/IDE or Equivalent | ||
Age-related macular degeneration, Vision Loss | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Stanford | Pre-IND/IDE or Equivalent | ||
Bladder or Urinary Tract Disorder, Incontinence, Skeletal/Smooth Muscle disorders | iPS Cell | Personalized cell therapy, Therapeutic Approach | Stanford | Pre-IND/IDE or Equivalent | ||
Intestinal Disease, Metabolic Disorders, Neurological Disorders, Pediatrics | iPS Cell | Donor cell therapy, Therapeutic Approach | CHLA | Pre-IND/IDE or Equivalent | ||
Autoimmune Disorder, Lupus, Systemic Lupus Erythematosus (SLE) | iPS Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | Fate Therapeutics | Clinical Trial, Phase 1 or Phase 1/2 | ||
Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML) | Somatic Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | Senti Bio | Clinical Trial, Phase 1 or Phase 1/2 | ||
Immune Disease | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | ImmPACT-Bio, Inc. | Clinical Trial, Phase 2 | |||
Blood Disorders | Somatic Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Nexcella, Inc. | Clinical Trial, Phase 1 or Phase 1/2 | ||
Brain Cancer, Cancer, Solid Tumors | Somatic Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSF | Clinical Trial, Phase 1 or Phase 1/2 | ||
Neurological Disorders, Parkinson's Disease | iPS Cell | Personalized cell therapy, Therapeutic Approach | Aspen Neuroscience | Clinical Trial, Phase 1 or Phase 1/2 | ||
Cancer, Solid Tumors | Somatic Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | Allogene Therapeutics | Clinical Trial, Phase 1 or Phase 1/2 | ||
Brain Cancer, Cancer, Solid Tumors | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCSF | Clinical Trial, Phase 1 or Phase 1/2 | |||
Age-related macular degeneration, Vision Loss | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Luxa Biotechnology | Clinical Trial, Phase 1 or Phase 1/2 | ||
Danon Disease, Metabolic Disorders, Pediatrics | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Rocket Pharmaceuticals, Inc. | Clinical Trial, Phase 2 | |||
Developmental Disorders, Neurological Disorders, Spina Bifida | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | UC Davis | Clinical Trial, Phase 2 | ||
Brain Cancer, Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | Clinical Trial, Phase 1 or Phase 1/2 | ||
Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML) | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | COH | Clinical Trial, Phase 1 or Phase 1/2 | |||
Neurological Disorders, Other | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | UCSD | Clinical Trial, Phase 1 or Phase 1/2 | |||
Cancer, Melanoma, Solid Tumors | Somatic Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | Clinical Trial, Phase 1 or Phase 1/2 | ||
Age-related macular degeneration, Vision Loss | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | Regenerative Patch Technologies LLC | Clinical Trial, Phase 2 | ||
HIV/AIDS, Infectious Disease | Other | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | COH | Clinical Trial, Phase 1 or Phase 1/2 | ||
Corneal Damage, Vision Loss | Adult or Tissue Stem Cell | Biologic, Exosomes based therapy, Therapeutic Approach | Combangio | Clinical Trial, Phase 2 | ||
Bone or Cartilage Disease, Hearing Loss, Intellectual Disability, Metabolic Disorders, Neurological Disorders, Vision Loss | Somatic Cell | Personalized cell therapy, Therapeutic Approach | Immusoft Corporation | Clinical Trial, Phase 1 or Phase 1/2 | ||
Cancer, Solid Tumors | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Eureka Therapeutics, Inc. | Clinical Trial, Phase 1 or Phase 1/2 | |||
Anemia, Blood Disorders | Adult or Tissue Stem Cell | Antibody, Biologic, Therapeutic Approach | Stanford | Clinical Trial, Phase 1 or Phase 1/2 | ||
B cell cancers, Blood Cancer, Cancer | Somatic Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | Angiocrine | Clinical Trial, Phase 3 | ||
Bone or Cartilage Disease, Osteoarthritis | Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Genascence Corporation | Clinical Trial, Phase 1 or Phase 1/2 | ||
Cancer, Colon Cancer, Solid Tumors | Tachyon Therapeutics, Inc | Clinical Trial, Phase 1 or Phase 1/2 | ||||
Anemia, Blood Disorders | Somatic Cell | Cell processing & handling, Immune tolerance/management, Technology | COH | Clinical Trial, Phase 1 or Phase 1/2 | ||
Anemia, Blood Disorders, Bone Marrow Transplant and Viral Infection | Adult or Tissue Stem Cell | Immune tolerance/management, Technology | Stanford | Clinical Trial, Phase 1 or Phase 1/2 | ||
Epilepsy, Neurological Disorders | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | Neurona Therapeutics | Clinical Trial, Phase 1 or Phase 1/2 | ||
HIV/AIDS, Infectious Disease | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Excision BioTherapeutics | Clinical Trial, Phase 1 or Phase 1/2 | |||
Bladder or Urinary Tract Disorder, Skeletal/Smooth Muscle disorders | Somatic Cell | Technology, Tissue engineering | Wake Forest University Health Sciences | Clinical Trial, Phase 1 or Phase 1/2 | ||
Blood Disorders, IPEX Syndrome | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | Clinical Trial, Phase 1 or Phase 1/2 | ||
Brain Cancer, Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | COH | Clinical Trial, Phase 1 or Phase 1/2 | ||
Muscle Injury, Skeletal/Smooth Muscle disorders | Adult or Tissue Stem Cell | Personalized cell therapy, Therapeutic Approach | UC Davis | Clinical Trial, Phase 1 or Phase 1/2 | ||
Cancer, Solid Tumors | Adult or Tissue Stem Cell | Personalized cell therapy, Therapeutic Approach | BioEclipse Therapeutics INC. | Clinical Trial, Phase 1 or Phase 1/2 | ||
Heart Disease, Heart failure | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | Stanford | Clinical Trial, Phase 1 or Phase 1/2 | ||
Brain Cancer, Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | Clinical Trial, Phase 1 or Phase 1/2 | ||
B cell cancers, Blood Cancer, Cancer, Leukemia, Leukemia, Acute Myeloid (AML) | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | Stanford | Clinical Trial, Phase 1 or Phase 1/2 | ||
Neurological Disorders, Stroke | Embryonic Stem Cell | Donor cell therapy, Therapeutic Approach | Stanford | Clinical Trial, Phase 1 or Phase 1/2 |