Year 2
Over the last year we have made significant progress on ability to differentiate stem cells towards a cell lineage that can help contribute to a functional thymus. We have been able to induce a number of key markers of thymic progenitor cells and are also making progress on experiments to confirm the functionality of the differentiated cells. Taken together, these results could have a broad and significant impact on the field of regenerative medicine due to the ability of the thymus to control immune tolerance.