Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment. 2024 Nat Commun
Custom-engineered hydrogels for delivery of human iPSC-derived neurons into the injured cervical spinal cord. 2024 Biomaterials
Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variation. 2024 Elife
Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin. 2024 Sci Adv
Generation of ‘semi-guided’ cortical organoids with complex neural oscillations. 2024 Nat Protoc
Generation of antigen-specific mature T cells from RAG1(-/-)RAG2(-/-)B2M(-/-) stem cells by engineering their microenvironment. 2024 Nat Biomed Eng
Harnessing Biomaterials to Amplify Immunity in Aged Mice through T Memory Stem Cells. 2024 ACS Nano
Locoregional delivery of IL-13Ralpha2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial. 2024 Nat Med
Non-invasive prenatal testing of beta-hemoglobinopathies using next generation sequencing, in-silico sequence size selection, and haplotyping. 2024 Croat Med J
Respiratory exposure to agricultural dust extract promotes increased intestinal Tnfalpha expression, gut barrier dysfunction, and endotoxemia in mice. 2024 Am J Physiol Gastrointest Liver Physiol
Secondary bone marrow graft loss after third-party virus-specific T cell infusion: Case report of a rare complication. 2024 Nat Commun
Small molecule inhibition of RNA binding proteins in haematologic cancer. 2024 RNA Biol
Stem cell-derived CAR T cells show greater persistence, trafficking, and viral control compared to ex vivo transduced CAR T cells. 2024 Mol Ther
Targeting IGF2BP3 enhances antileukemic effects of menin-MLL inhibition in MLL-AF4 leukemia. 2024 Blood Adv
Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy. 2024 Neuron
[Cystinosis: From the gene identification to the first gene therapy clinical trial]. 2023 Med Sci (Paris)
A bio-instructive parylene-based conformal coating suppresses thrombosis and intimal hyperplasia of implantable vascular devices. 2023 Bioact Mater
A bioactive material with dual integrin-targeting ligands regulates specific endogenous cell adhesion and promotes vascularized bone regeneration in adult and fetal bone defects. 2023 Bioact Mater
A covalent inhibitor of the YAP-TEAD transcriptional complex identified by high-throughput screening. 2023 RSC Chem Biol
A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization. 2023 J Invest Dermatol
A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa. 2023 bioRxiv
A spatially resolved single-cell genomic atlas of the adult human breast. 2023 Nature
Abrupt perturbation and delayed recovery of the vaginal ecosystem following childbirth. 2023 Nat Commun
Allele-specific expression reveals genetic drivers of tissue regeneration in mice. 2023 Cell Stem Cell
An altered extracellular matrix-integrin interface contributes to Huntington’s disease-associated CNS dysfunction in glial and vascular cells. 2023 Hum Mol Genet
An Inexpensive 3D Printed Mouse Model of Successful, Complication-free Long Bone Distraction Osteogenesis. 2023 Plast Reconstr Surg Glob Open
An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis. 2023 Commun Biol
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting. 2023 Nat Commun
Antiretrovirals to CCR5 CRISPR/Cas9 gene editing – A paradigm shift chasing an HIV cure. 2023 Clin Immunol
Assaying Chemical Long-Term Potentiation in Human iPSC-Derived Neuronal Networks. 2023 Methods Mol Biol
Attenuating Chronic Fibrosis: Decreasing Foreign Body Response with Acellular Dermal Matrix. 2023 Tissue Eng Part B Rev
Automated 384-well SYBR Green Expression Array for Optimization of Human Induced Pluripotent Stem Cell Differentiation. 2023 Bio Protoc
Biodegradable nanoparticles targeting circulating immune cells reduce central and peripheral sensitization to alleviate neuropathic pain following spinal cord injury. 2023 Pain
Bridging the gap with bacterial art. 2023 FEMS Microbiol Lett
Broadly neutralizing antibodies targeting HIV: Progress and challenges. 2023 Clin Immunol
CD203c is expressed by human fetal hepatoblasts and distinguishes subsets of hepatoblastoma. 2023 Front Oncol
Cellular Therapy for Children with Central Nervous System Tumors: Mining and Mapping the Correlative Data. 2023 Curr Oncol Rep
Combination of Distinct Vascular Stem/Progenitor Cells for Neovascularization and Ischemic Rescue. 2023 Arterioscler Thromb Vasc Biol
Comparative analysis between single-cell RNA-seq and single-molecule RNA FISH indicates that the pyrimidine nucleobase idoxuridine (IdU) globally amplifies transcriptional noise. 2023 bioRxiv
Complex urban atmosphere alters alveolar stem cells niche properties and drives lung fibrosis. 2023 Am J Physiol Lung Cell Mol Physiol
Conductive electrospun polymer improves stem cell-derived cardiomyocyte function and maturation. 2023 Biomaterials
Context matters: hPSC-derived microglia thrive in a humanized brain environment in vivo. 2023 Cell Stem Cell
Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation. 2023 Elife
Craniofacial developmental biology in the single-cell era. 2023 Development
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. 2023 Nat Commun
Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence. 2023 Elife
Developing a human iPSC-derived three-dimensional myelin spheroid platform for modeling myelin diseases. 2023 iScience
Developing Hypoimmunogenic Human iPSC-Derived Oligodendrocyte Progenitor Cells as an Off-The-Shelf Cell Therapy for Myelin Disorders. 2023 Adv Sci (Weinh)
DNA Methylation Dynamics During Esophageal Epithelial Regeneration Following Repair with Acellular Silk Fibroin Grafts in Rat. 2023 Adv Biol (Weinh)
Efficient manufacturing and engraftment of CCR5 gene-edited HSPCs following busulfan conditioning in nonhuman primates. 2023 Mol Ther Methods Clin Dev
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