Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
A Single CRISPR-Cas9 Deletion Strategy that Targets the Majority of DMD Patients Restores Dystrophin Function in hiPSC-Derived Muscle Cells. 2016 Cell Stem Cell
A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting. 2016 Nat Commun
A ventral root avulsion injury model for neurogenic underactive bladder studies. 2016 Exp Neurol
Activating Hair Follicle Stem Cells via R-spondin2 to Stimulate Hair Growth. 2016 J Invest Dermatol
Adult Stem Cell Therapy and Heart Failure, 2000 to 2016: A Systematic Review. 2016 JAMA Cardiol
Aggregate formation and suspension culture of human pluripotent stem cells and differentiated progeny. 2016 Methods
Alcohol-induced suppression of KDM6B dysregulates the mineralization potential in dental pulp stem cells. 2016 Stem Cell Res
alpha-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells. 2016 Cell Metab
alphaB-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition. 2016 Am J Pathol
alphaE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth development. 2016 Nat Commun
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. 2016 Mol Psychiatry
An artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy. 2016 Nat Biotechnol
An atlas of transcriptional, chromatin accessibility, and surface marker changes in human mesoderm development. 2016 Sci Data
An Innovative Surgical Technique for Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium in Yucatan Mini Pigs: Preliminary Results. 2016 Ophthalmic Surg Lasers Imaging Retina
An Overview of Direct Somatic Reprogramming: The Ins and Outs of iPSCs. 2016 Int J Mol Sci
Anatomical and Gene Expression Changes in the Retinal Pigmented Epithelium Atrophy 1 (rpea1) Mouse: A Potential Model of Serous Retinal Detachment. 2016 Invest Ophthalmol Vis Sci
Assessing the therapeutic potential of lab-made hepatocytes. 2016 Hepatology
Autonomous Extracellular Matrix Remodeling Controls a Progressive Adaptation in Muscle Stem Cell Regenerative Capacity during Development. 2016 Cell Rep
Axin2-expressing cells execute regeneration after skeletal injury. 2016 Sci Rep
Bio-Orthogonally Crosslinked, Engineered Protein Hydrogels with Tunable Mechanics and Biochemistry for Cell Encapsulation. 2016 Adv Funct Mater
Biological impact of xeno-free chemically defined cryopreservation medium on amniotic epithelial cells. 2016 Stem Cell Res Ther
Bradykinin promotes neuron-generating division of neural progenitor cells through ERK activation. 2016 J Cell Sci
Brief Report: Immune Microenvironment Determines the Immunogenicity of Induced Pluripotent Stem Cell Derivatives. 2016 Stem Cells
CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells. 2016 Stem Cell Reports
Cells with surface expression of CD133(high)CD71(low) are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas. 2016 Stem Cell Res
Chromosome conformation elucidates regulatory relationships in developing human brain. 2016 Nature
Circular RNA profile in gliomas revealed by identification tool UROBORUS. 2016 Nucleic Acids Res
Cockayne Syndrome-derived neurons display reduced synapse density and altered neural network synchrony. 2016 Hum Mol Genet
Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering. 2016 Acta Biomater
Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes. 2016 Brain Res
Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas. 2016 Stem Cell Reports
Competition between Jagged-Notch and Endothelin1 Signaling Selectively Restricts Cartilage Formation in the Zebrafish Upper Face. 2016 PLoS Genet
Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling. 2016 Stem Cells
Concise Review: Paracrine Functions of Vascular Niche Cells in Regulating Hematopoietic Stem Cell Fate. 2016 Stem Cells Transl Med
Constructing 3D interaction maps from 1D epigenomes. 2016 Nat Commun
Conversion of human fibroblasts into functional cardiomyocytes by small molecules. 2016 Science
Correction: Identification of Androgen Receptor Splice Variants in the Pten Deficient Murine Prostate Cancer Model. 2016 PLoS One
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. 2016 Nat Biotechnol
CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. 2016 Cell Stem Cell
Culturing Human Pluripotent and Neural Stem Cells in an Enclosed Cell Culture System for Basic and Preclinical Research. 2016 J Vis Exp
Deletion of the Imprinted Gene Grb10 Promotes Hematopoietic Stem Cell Self-Renewal and Regeneration. 2016 Cell Rep
Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation. 2016 Science
Design Principles for Engineering of Tissues from Human Pluripotent Stem Cells. 2016 Curr Stem Cell Rep
Development of the Mammalian Kidney. 2016 Curr Top Dev Biol
Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators. 2016 Development
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros. 2016 Nat Biotechnol
Direct 3D-printing of cell-laden constructs in microfluidic architectures. 2016 Lab Chip
Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq. 2016 Nature
Distal airway epithelial progenitor cells are radiosensitive to High-LET radiation. 2016 Sci Rep
Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. 2016 Nat Commun