Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions. 2016 Cell Rep
Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis. 2016 JCI Insight
Dysregulated endocardial TGFbeta signaling and mesenchymal transformation result in heart outflow tract septation failure. 2016 Dev Biol
Effects of Human ES-Derived Neural Stem Cell Transplantation and Kindling in a Rat Model of Traumatic Brain Injury. 2016 Cell Transplant
Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies. 2016 Adv Drug Deliv Rev
Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival. 2016 Cell Rep
Enhanced phasic GABA inhibition during the repair phase of stroke: a novel therapeutic target. 2016 Brain
ERRgamma Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive beta Cells. 2016 Cell Metab
Evaluating Cell Processes, Quality, and Biomarkers in Pluripotent Stem Cells Using Video Bioinformatics. 2016 PLoS One
Existence of Normal Limbal Epithelium in Eyes With Clinical Signs of Total Limbal Stem Cell Deficiency. 2016 Cornea
Extensive migration of young neurons into the infant human frontal lobe. 2016 Science
From the Cover: Thirdhand Cigarette Smoke Causes Stress-Induced Mitochondrial Hyperfusion and Alters the Transcriptional Profile of Stem Cells. 2016 Toxicol Sci
Functional Human and Murine Tissue-Engineered Liver Is Generated From Adult Stem/Progenitor Cells. 2016 Stem Cells Transl Med
Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson’s Disease. 2016 Cell Stem Cell
Gene expression changes in the retina following subretinal injection of human neural progenitor cells into a rodent model for retinal degeneration. 2016 Mol Vis
Generation and Characterization of Patient-Specific Induced Pluripotent Stem Cell for Disease Modeling. 2016 Methods Mol Biol
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors. 2016 Stem Cells
Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice. 2016 J Assoc Res Otolaryngol
Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease. 2016 Nat Commun
Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State. 2016 Cell Stem Cell
Haploinsufficiency of BAZ1B contributes to Williams syndrome through transcriptional dysregulation of neurodevelopmental pathways. 2016 Hum Mol Genet
Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy. 2016 Sci Transl Med
High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo. 2016 Nat Commun
High-Resolution Microfluidic Single-Cell Transcriptional Profiling Reveals Clinically Relevant Subtypes among Human Stem Cell Populations Commonly Utilized in Cell-Based Therapies. 2016 Front Neurol
HIV-1-Specific Chimeric Antigen Receptors Based on Broadly Neutralizing Antibodies. 2016 J Virol
Human and Murine Tissue-Engineered Colon Exhibit Diverse Neuronal Subtypes and Can Be Populated by Enteric Nervous System Progenitor Cells When Donor Colon Is Aganglionic. 2016 Tissue Eng Part A
Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis. 2016 Biol Reprod
Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington’s disease Mouse Models. 2016 Mol Ther
Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease. 2016 Proc Natl Acad Sci U S A
Hyaluronan as a therapeutic target in human diseases. 2016 Adv Drug Deliv Rev
Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis. 2016 Matrix Biol
Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer. 2016 Cell Rep
Identifying gene expression modules that define human cell fates. 2016 Stem Cell Res
IGF1 neuronal response in the absence of MECP2 is dependent on TRalpha 3. 2016 Hum Mol Genet
Immunosuppressive Treatment Can Alter Visual Performance in the RCS Rat. 2016 J Ocul Pharmacol Ther
Improved Mobilization of Exogenous Mesenchymal Stem Cells to Bone for Fracture Healing and Sex Difference. 2016 Stem Cells
In vivo blunt-end cloning through CRISPR/Cas9-facilitated non-homologous end-joining. 2016 Nucleic Acids Res
In Vivo Hepatic Reprogramming of Myofibroblasts with AAV Vectors as a Therapeutic Strategy for Liver Fibrosis. 2016 Cell Stem Cell
Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance. 2016 Mol Cancer Res
Increased Gs Signaling in Osteoblasts Reduces Bone Marrow and Whole-Body Adiposity in Male Mice. 2016 Endocrinology
Incubator embedded cell culture imaging system (EmSight) based on Fourier ptychographic microscopy. 2016 Biomed Opt Express
Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods. 2016 J Ocul Pharmacol Ther
Induction of site-specific chromosomal translocations in embryonic stem cells by CRISPR/Cas9. 2016 Sci Rep
Inferring causal molecular networks: empirical assessment through a community-based effort. 2016 Nat Methods
Influence of Intermittent Preventive Treatment on Antibodies to VAR2CSA in Pregnant Cameroonian Women. 2016 Am J Trop Med Hyg
Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos. 2016 Cell Stem Cell
Integrating Concepts of Material Mechanics, Ligand Chemistry, Dimensionality and Degradation to Control Differentiation of Mesenchymal Stem Cells. 2016 Curr Opin Solid State Mater Sci
Intronic polyadenylation of PDGFRalpha in resident stem cells attenuates muscle fibrosis. 2016 Nature
Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells. 2016 Mol Ther Methods Clin Dev
Ischemia as a factor affecting innate immune responses in kidney transplantation. 2016 Curr Opin Nephrol Hypertens