Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome. 2016 Proc Natl Acad Sci U S A
Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction. 2016 Proc Natl Acad Sci U S A
Light-Patterned RNA Interference of 3D-Cultured Human Embryonic Stem Cells. 2016 Adv Mater
Linking suckling biomechanics to the development of the palate. 2016 Sci Rep
Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness. 2016 J Cell Biol
Magnetic Resonance Imaging of Cardiac Strain Pattern Following Transplantation of Human Tissue Engineered Heart Muscles. 2016 Circ Cardiovasc Imaging
Magnetic Resonance Imaging of Iron Oxide-Labeled Human Embryonic Stem Cell-Derived Cardiac Progenitors. 2016 Stem Cells Transl Med
Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types. 2016 Cell
Maternal Human Immunodeficiency Virus-Associated Hypergammaglobulinemia Reduces Transplacental Transfer of Immunoglobulin G to Plasmodium falciparum Antigens in Cameroonian Neonates. 2016 Open Forum Infect Dis
Measurements of absolute concentrations of NADH in cells using the phasor FLIM method. 2016 Biomed Opt Express
Mechanical Control of Epithelial-to-Mesenchymal Transitions in Development and Cancer. 2016 Annu Rev Cell Dev Biol
Mechanoresponsive Properties of the Periodontal Ligament. 2016 J Dent Res
Medial HOXA genes demarcate haematopoietic stem cell fate during human development. 2016 Nat Cell Biol
Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward. 2016 J Neurosci
Mesenchymal stem cells engineered to express selectin ligands and IL-10 exert enhanced therapeutic efficacy in murine experimental autoimmune encephalomyelitis. 2016 Biomaterials
Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA. 2016 Mol Cell
Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. 2016 Sci Rep
Mitochondria in human pluripotent stem cell apoptosis. 2016 Semin Cell Dev Biol
Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells. 2016 Cell Metab
Modeling autism spectrum disorders with human neurons. 2016 Brain Res
Modifying the Mitochondrial Genome. 2016 Cell Metab
Monitoring developmental force distributions in reconstituted embryonic epithelia. 2016 Methods
Msx1 and Msx2 function together in the regulation of primordial germ cell migration in the mouse. 2016 Dev Biol
Multifactorial Optimizations for Directing Endothelial Fate from Stem Cells. 2016 PLoS One
Multifocus microscopy with precise color multi-phase diffractive optics applied in functional neuronal imaging. 2016 Biomed Opt Express
Multiparameter evaluation of in vivo gene delivery using ultrasound-guided, microbubble-enhanced sonoporation. 2016 J Control Release
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells. 2016 Nature
N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells. 2016 Cancer Cell
Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory. 2016 Cell Stem Cell
NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism. 2016 Cell Metab
Nanoparticle engineered TRAIL-overexpressing adipose-derived stem cells target and eradicate glioblastoma via intracranial delivery. 2016 Proc Natl Acad Sci U S A
Neurorestoration after stroke. 2016 Neurosurg Focus
Non-invasive Chamber-Specific Identification of Cardiomyocytes in Differentiating Pluripotent Stem Cells. 2016 Stem Cell Reports
Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate. 2016 Stem Cell Reports
Nuclear transfer nTreg model reveals fate-determining TCR-beta and novel peripheral nTreg precursors. 2016 Proc Natl Acad Sci U S A
ONE-CLASS DETECTION OF CELL STATES IN TUMOR SUBTYPES. 2016 Pac Symp Biocomput
p53 Regulates Progenitor Cell Quiescence and Differentiation in the Airway. 2016 Cell Rep
P53 Regulates Rapid Apoptosis in Human Pluripotent Stem Cells. 2016 J Mol Biol
Pancreatic Tissue Transplanted in TheraCyte Encapsulation Devices Is Protected and Prevents Hyperglycemia in a Mouse Model of Immune-Mediated Diabetes. 2016 Cell Transplant
Paramagnetic fluorinated nanoemulsions for sensitive cellular fluorine-19 magnetic resonance imaging. 2016 Nat Mater
Pathway-Based Genomics Prediction using Generalized Elastic Net. 2016 PLoS Comput Biol
Patterns of expression of factor VIII and von Willebrand factor by endothelial cell subsets in vivo. 2016 Blood
Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer. 2016 Cell
Placental transcriptomes in the common aneuploidies reveal critical regions on the trisomic chromosomes and genome-wide effects. 2016 Prenat Diagn
Pluripotent Stem Cell-Based Therapies in Combination with Substrate for the Treatment of Age-Related Macular Degeneration. 2016 J Ocul Pharmacol Ther
Potent spinal parenchymal AAV9-mediated gene delivery by subpial injection in adult rats and pigs. 2016 Mol Ther Methods Clin Dev
Potential Strategies to Address the Major Clinical Barriers Facing Stem Cell Regenerative Therapy for Cardiovascular Disease: A Review. 2016 JAMA Cardiol
Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice. 2016 PLoS One
Precise Correction of Disease Mutations in Induced Pluripotent Stem Cells Derived From Patients With Limb Girdle Muscular Dystrophy. 2016 Mol Ther
Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells. 2016 Mol Ther Methods Clin Dev