Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis. 2016 J Clin Invest
Transcriptome Encyclopedia of Early Human Development. 2016 Cell
Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro. 2016 Cell Stem Cell
Transplantation of human neural stem cells restores cognition in an immunodeficient rodent model of traumatic brain injury. 2016 Exp Neurol
Transplanted Human Stem Cell-Derived Interneuron Precursors Mitigate Mouse Bladder Dysfunction and Central Neuropathic Pain after Spinal Cord Injury. 2016 Cell Stem Cell
Tuning microenvironment modulus and biochemical composition promotes human mesenchymal stem cell tenogenic differentiation. 2016 J Biomed Mater Res A
Vascular Endothelial Growth Factor (VEGF) Bioavailability Regulates Angiogenesis and Intestinal Stem and Progenitor Cell Proliferation during Postnatal Small Intestinal Development. 2016 PLoS One
Vertical sleeve gastrectomy activates GPBAR-1/TGR5 to sustain weight loss, improve fatty liver, and remit insulin resistance in mice. 2016 Hepatology
Whole-genome mutational burden analysis of three pluripotency induction methods. 2016 Nat Commun
Wnt/beta-catenin and LIF-Stat3 signaling pathways converge on Sp5 to promote mouse embryonic stem cell self-renewal. 2016 J Cell Sci
YAP Induces Human Naive Pluripotency. 2016 Cell Rep
1,5-Disubstituted benzimidazoles that direct cardiomyocyte differentiation from mouse embryonic stem cells. 2015 Bioorg Med Chem
A basal stem cell signature identifies aggressive prostate cancer phenotypes. 2015 Proc Natl Acad Sci U S A
A Continuous Molecular Roadmap to iPSC Reprogramming through Progression Analysis of Single-Cell Mass Cytometry. 2015 Cell Stem Cell
A functional genomics screen identifies an Importin-alpha homolog as a regulator of stem cell function and tissue patterning during planarian regeneration. 2015 BMC Genomics
A new notch for lung stem cells. 2015 Cell Stem Cell
A novel profibrotic mechanism mediated by TGFbeta-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells. 2015 J Pathol
A novel, long-lived, and highly engraftable immunodeficient mouse model of mucopolysaccharidosis type I. 2015 Mol Ther Methods Clin Dev
A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics. 2015 Elife
A platform for rapid generation of single and multiplexed reporters in human iPSC lines. 2015 Sci Rep
A quantitative assessment of the content of hematopoietic stem cells in mouse and human endosteal-bone marrow: a simple and rapid method for the isolation of mouse central bone marrow. 2015 BMC Hematol
A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy. 2015 Stem Cell Reports
A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation. 2015 Elife
A survey of human brain transcriptome diversity at the single cell level. 2015 Proc Natl Acad Sci U S A
Adaptable hydrogel networks with reversible linkages for tissue engineering. 2015 Adv Mater
Adipogenesis and epicardial adipose tissue: a novel fate of the epicardium induced by mesenchymal transformation and PPARgamma activation. 2015 Proc Natl Acad Sci U S A
Adult stem-like cells exclude “older” mitochondria. 2015 Cell Metab
Age Does Matter: A Pilot Comparison of Placenta-Derived Stromal Cells for in utero Repair of Myelomeningocele Using a Lamb Model. 2015 Fetal Diagn Ther
Altered iPSC-derived neurons’ sodium channel properties in subjects with Monge’s disease. 2015 Neuroscience
Altered neuronal network and rescue in a human MECP2 duplication model. 2015 Mol Psychiatry
An estrogen-responsive module in the ventromedial hypothalamus selectively drives sex-specific activity in females. 2015 Cell Rep
Analysis of a transgenic Oct4 enhancer reveals high fidelity long-range chromosomal interactions. 2015 Sci Rep
Arrhythmia in stem cell transplantation. 2015 Card Electrophysiol Clin
beta2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis. 2015 Nat Med
Bilayered vascular graft derived from human induced pluripotent stem cells with biomimetic structure and function. 2015 Regen Med
Bioactivity and Safety of IL13Ralpha2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma. 2015 Clin Cancer Res
Brahma is required for cell cycle arrest and late muscle gene expression during skeletal myogenesis. 2015 EMBO Rep
Breast Cancer beyond the Age of Mutation. 2015 Gerontology
Brief Report: Oxidative Stress Mediates Cardiomyocyte Apoptosis in a Human Model of Danon Disease and Heart Failure. 2015 Stem Cells
Brief reports: Lysosomal cross-correction by hematopoietic stem cell-derived macrophages via tunneling nanotubes. 2015 Stem Cells
Calibrated forceps model of spinal cord compression injury. 2015 J Vis Exp
Canonical/beta-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells. 2015 Invest Ophthalmol Vis Sci
Cardiac extracellular matrix proteomics: Challenges, techniques, and clinical implications. 2015 Proteomics Clin Appl
CBP/catenin antagonist safely eliminates drug-resistant leukemia-initiating cells. 2015 Oncogene
CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia. 2015 Cell Stem Cell
Cell-fate determination by ubiquitin-dependent regulation of translation. 2015 Nature
Cellular models and therapies for age-related macular degeneration. 2015 Dis Model Mech
Cellular postconditioning: allogeneic cardiosphere-derived cells reduce infarct size and attenuate microvascular obstruction when administered after reperfusion in pigs with acute myocardial infarction. 2015 Circ Heart Fail
Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation. 2015 Elife
Comparison of the specificity of antibodies to VAR2CSA in Cameroonian multigravidae with and without placental malaria: a retrospective case-control study. 2015 Malar J