Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Making Heads or Tails of the Large Mammalian Sinoatrial Node Micro-Organization. 2021 Circ Arrhythm Electrophysiol
Mesenchymal Stromal Cells Regulate Sialylations of N-Glycans, Affecting Cell Migration and Survival. 2021 Int J Mol Sci
Metallofluorocarbon Nanoemulsion for Inflammatory Macrophage Detection via PET and MRI. 2021 J Nucl Med
Minimizing the risk of occupational Q fever exposure: A protocol for ensuring Coxiella burnetii-negative pregnant ewes are used for medical research. 2021 Lab Anim
Mitochondria as Playmakers of CAR T-cell Fate and Longevity. 2021 Cancer Immunol Res
Modeling preeclampsia using human induced pluripotent stem cells. 2021 Sci Rep
Multiple Treatment Cycles of Neural Stem Cell Delivered Oncolytic Adenovirus for the Treatment of Glioblastoma. 2021 Cancers (Basel)
N-terminal deletion of specific phosphorylation sites on PHOX2B disrupts the formation of enteric neurons in vivo. 2021 Am J Physiol Gastrointest Liver Physiol
Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease. 2021 Science
Non-invasive intradermal imaging of cystine crystals in cystinosis. 2021 PLoS One
Non-Invasive Prenatal Test for beta-Thalassemia and Sickle Cell Disease Using Probe Capture Enrichment and Next-Generation Sequencing of DNA in Maternal Plasma. 2021 J Appl Lab Med
Normal IgH Repertoire Diversity in an Infant with ADA Deficiency After Gene Therapy. 2021 J Clin Immunol
Organophosphate Flame Retardants, Highly Fluorinated Chemicals, and Biomarkers of Placental Development and Disease During Mid-Gestation. 2021 Toxicol Sci
Overexpression of CD47 is associated with brain overgrowth and 16p11.2 deletion syndrome. 2021 Proc Natl Acad Sci U S A
Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents. 2021 Sci Transl Med
peri-Adventitial delivery of smooth muscle cells in porous collagen scaffolds for treatment of experimental abdominal aortic aneurysm. 2021 Biomater Sci
Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids. 2021 EMBO Mol Med
Placental Mesenchymal Stromal Cells: Preclinical Safety Evaluation for Fetal Myelomeningocele Repair. 2021 J Surg Res
Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring. 2021 Science
Proangiogenic Collagen-Binding Glycan Therapeutic Promotes Endothelial Cell Angiogenesis. 2021 ACS Biomater Sci Eng
Regeneration of Jaw Joint Cartilage in Adult Zebrafish. 2021 Front Cell Dev Biol
Regulation of Limbal Epithelial Stem Cells: Importance of the Niche. 2021 Int J Mol Sci
Reliable generation of glial enriched progenitors from human fibroblast-derived iPSCs. 2021 Stem Cell Res
Repeatability of tumor perfusion kinetics from dynamic contrast-enhanced MRI in glioblastoma. 2021 Neurooncol Adv
Retinal Organoids Long-Term Functional Characterization Using Two-Photon Fluorescence Lifetime and Hyperspectral Microscopy. 2021 Front Cell Neurosci
Retinal organoids on-a-chip: a micro-millifluidic bioreactor for long-term organoid maintenance. 2021 Lab Chip
Retinal Protection by Sustained Nanoparticle Delivery of Oncostatin M and Ciliary Neurotrophic Factor Into Rodent Models of Retinal Degeneration. 2021 Transl Vis Sci Technol
Reversing neural circuit and behavior deficit in mice exposed to maternal inflammation by Zika virus. 2021 EMBO Rep
Robust CAR-T memory formation and function via hematopoietic stem cell delivery. 2021 PLoS Pathog
SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery. 2021 Cell Rep
Secretomes of human pluripotent stem cell-derived smooth muscle cell progenitors upregulate extracellular matrix metabolism in the lower urinary tract and vagina. 2021 Stem Cell Res Ther
Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption. 2021 Cell Stem Cell
Signaling Pathways That Regulate Normal and Aberrant Red Blood Cell Development. 2021 Genes (Basel)
Skeletal stem and progenitor cells maintain cranial suture patency and prevent craniosynostosis. 2021 Nat Commun
Stem cell-derived CAR T cells traffic to HIV reservoirs in macaques. 2021 JCI Insight
Successful SCID gene therapy in infant with disseminated BCG. 2021 J Allergy Clin Immunol Pract
Superporous agarose scaffolds for encapsulation of adult human islets and human stem-cell-derived beta cells for intravascular bioartificial pancreas applications. 2021 J Biomed Mater Res A
Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells. 2021 Cell Stem Cell
Targeting PUS7 suppresses tRNA pseudouridylation and glioblastoma tumorigenesis. 2021 Nat Cancer
The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D. 2021 Nature
The developing mouse coronal suture at single-cell resolution. 2021 Nat Commun
The Epithelial-Mesenchymal Transcription Factor SNAI1 Represses Transcription of the Tumor Suppressor miRNA let-7 in Cancer. 2021 Cancers (Basel)
The Rhox gene cluster suppresses germline LINE1 transposition. 2021 Proc Natl Acad Sci U S A
The Unique Properties of Placental Mesenchymal Stromal Cells: A Novel Source of Therapy for Congenital and Acquired Spinal Cord Injury. 2021 Cells
Therapeutic implications of transplanted-cell death. 2021 Nat Biomed Eng
Upregulation of Vitamin C Transporter Functional Expression in 5xFAD Mouse Intestine. 2021 Nutrients
Vitamin C, From Supplement to Treatment: A Re-Emerging Adjunct for Cancer Immunotherapy? 2021 Front Immunol
Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine. 2021 RSC Chem Biol
Wnt6 plays a complex role in maintaining human limbal stem/progenitor cells. 2021 Sci Rep
A critical look: Challenges in differentiating human pluripotent stem cells into desired cell types and organoids. 2020 Wiley Interdiscip Rev Dev Biol