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Institution
Researcher name
Grant Type
Grant Title
Award Value
University of Southern California
Dr. Neil Segil
Quest – Discovery Stage Research Projects
A screen for drugs to protect against chemotherapy-induced hearing loss, using sensory hair cells derived by direct lineage reprogramming from hiPSCs
$741,574
Salk Institute for Biological Studies
Ronald Mark Evans
Quest – Discovery Stage Research Projects
Therapeutic immune tolerant human islet-like organoids (HILOs) for Type 1 Diabetes
$1,637,209
Gladstone Institutes, J. David
Li Gan
Quest – Discovery Stage Research Projects
Develop iPSC-derived microglia to treat progranulin-deficient Frontotemporal Dementia
$1,547,157
University of California, Los Angeles
Dr. Lili Yang
Quest – Discovery Stage Research Projects
Preclinical Development of An HSC-Engineered Off-The-Shelf iNKT Cell Therapy for Cancer
$1,404,000
University of California, San Diego
Dr. Eric D. Adler MD
Quest – Discovery Stage Research Projects
Genetically Modified Hematopoietic Stem Cells for the Treatment of Danon Disease
$1,393,200
Stanford University
Dr. Katja Weinacht
Quest – Discovery Stage Research Projects
Regenerative Thymic Tissues as Curative Cell Therapy for Patients with 22q11 Deletion Syndrome
$1,251,720
City of Hope, Beckman Research Institute
Dr Saul J Priceman
Quest – Discovery Stage Research Projects
Chimeric Antigen Receptor-Engineered Stem/Memory T Cells for the Treatment of Recurrent Ovarian Cancer
$1,351,174
Stanford University
Dr. Philip Arden Beachy PhD
Quest – Discovery Stage Research Projects
Pluripotent stem cell-derived bladder epithelial progenitors for definitive cell replacement therapy of bladder cancer
$1,265,436
Scripps Research Institute
Stuart A Lipton
Quest – Discovery Stage Research Projects
Drug Development for Autism Spectrum Disorder Using Human Patient iPSCs
$1,827,576
University of California, San Francisco
Dr. Hideho Okada
Quest – Discovery Stage Research Projects
Non-viral reprogramming of the endogenous TCRα locus to direct stem memory T cells against shared neoantigens in malignant gliomas
$900,000
Children’s Hospital of Los Angeles
Dr. Mark R Frey
Quest – Discovery Stage Research Projects
Universal Pluripotent Liver Failure Therapy (UPLiFT)
$1,297,512
University of California, San Diego
Dr. Jonathan H Lin
Quest – Discovery Stage Research Projects
Small Molecule Proteostasis Regulators to Treat Photoreceptor Diseases
$1,153,937
University of California, Irvine
Dr. Aileen J Anderson
Quest – Discovery Stage Research Projects
Generation and in vitro profiling of neural stem cell lines to predict in vivo efficacy for chronic cervical spinal cord injury.
$1,575,613
University of California, San Francisco
Dr. Shuvo Roy
Quest – Discovery Stage Research Projects
Silicon Nanopore Membrane encapsulated enriched-Beta Clusters for Type 1 Diabetes treatment
$1,113,000
University of California, Los Angeles
Dr. Scott G Kitchen
Quest – Discovery Stage Research Projects
Engineering Lifelong Cellular Immunity to HIV
$1,701,178
University of California, San Diego
Dr. Tannishtha Reya
Quest – Discovery Stage Research Projects
Targeting Cancer Stem Cells in Hematologic Malignancies
$1,960,560
University of California, Los Angeles
Dr. Thomas Carmichael M.D., Ph.D.
Quest – Discovery Stage Research Projects
iPS Glial Therapy for White Matter Stroke and Vascular Dementia
$2,086,130
University of California, Los Angeles
Dr. April Pyle Ph.D.
Quest – Discovery Stage Research Projects
Identification and Generation of Long Term Repopulating Human Muscle Stem Cells from Human Pluripotent Stem Cells
$2,148,519
Stanford University
Dr. Kyle M Loh
Quest – Discovery Stage Research Projects
Towards hepatocyte cell replacement therapy: developing a renewable source of human hepatocytes from pluripotent stem cells
$1,968,456
University of California, San Diego
Mark H Tuszynski
Quest – Discovery Stage Research Projects
Neural Stem Cell Relays for Severe Spinal Cord Injury
$1,638,900
Stanford University
Dr. Helen M Blau
Quest – Discovery Stage Research Projects
Stimulating endogenous muscle stem cells to counter muscle atrophy
$2,198,687
ViaCyte, Inc.
Dr. Alan D. Agulnick
Quest – Discovery Stage Research Projects
Preclinical development of an immune evasive islet cell replacement therapy for type 1 diabetes
$1,470,987
University of California, San Diego
Dr Yang Xu
Quest – Discovery Stage Research Projects
Development of immune invisible beta cells as a cell therapy for type 1 diabetes through genetic modification of hESCs
$1,924,791
Neurona Therapeutics
Dr. Cory R Nicholas
Quest – Discovery Stage Research Projects
Development of a Cellular Therapeutic for Treatment of Epilepsy
$1,616,536
City of Hope, Beckman Research Institute
Dr. Saswati Chatterjee
Quest – Discovery Stage Research Projects
Genome Editing of Sinusoidal Endothelial Stem Cells for Permanent Correction of Hemophilia A
$2,182,193
University of California, Irvine
Dr. Brian J. Cummings
Quest – Discovery Stage Research Projects
Identification and characterization of the optimal human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) 2.0.
$1,671,213
University of California, Los Angeles
Dr. Vaithilingaraja Arumugaswami PhD
Quest – Discovery Stage Research Projects
Immunization strategies to prevent Zika viral congenital eye and brain disease
$2,128,867
Rumi Scientific CA
Ali H. Brivanlou
Quest – Discovery Stage Research Projects
Discovery of therapeutics for Huntington’s Disease
$1,399,800
University of California, Los Angeles
UCLA Gay M Crooks
Quest – Discovery Stage Research Projects
Platform Technology for Pluripotent Stem Cell-Derived T cell Immunotherapy
$965,636
X-Therma Inc.
Dr. Xiaoxi Wei
Quest – Discovery Stage Research Projects
Non-Toxic, Highly-Effective Bioinspired Cryoprotectants for On-Demand Stem Cell Therapies
$887,883
University of California, Los Angeles
Dr. Caroline Y. Kuo
Quest – Discovery Stage Research Projects
Targeted Gene Editing in the Treatment of X-Linked Hyper-IgM Syndrome
$1,512,333
University of California, Davis
Dr. Deborah K Lieu
Quest – Discovery Stage Research Projects
Microenvironment for hiPSC-derived pacemaking cardiomyocytes
$2,042,438
Stanford University
Dr. Mark Mercola
Quest – Discovery Stage Research Projects
Multipotent Cardiovascular Progenitor Regeneration of the Myocardium after MI
$1,809,234
University of California, San Diego
Professor Yuan Chen
Quest – Discovery Stage Research Projects
A Novel Approach to Eradicate Cancer Stem Cells
$279,977
City of Hope, Beckman Research Institute
Professor Yuan Chen
Quest – Discovery Stage Research Projects
A Novel Approach to Eradicate Cancer Stem Cells
$1,539,935
University of California, Berkeley
5106433559 Kevin E. Healy
Quest – Discovery Stage Research Projects
Human Cardiac Chip for Assessment of Proarrhythmic Risk
$899,581
University of California, San Francisco
Dr. Holger F Willenbring
Quest – Discovery Stage Research Projects
Preclinical development of AAV vector-mediated in vivo hepatic reprogramming of myofibroblasts as a therapy for liver fibrosis
$1,638,389
Scaled Biolabs Inc.
Dr Justin Cooper-White
Quest – Discovery Stage Research Projects
A tool for rapid development of clinical-grade protocols for dopaminergic neuronal differentiation of Parkinson’s Disease patient-derived iPSCs
$657,528
City of Hope, Beckman Research Institute
Markus Müschen
Quest – Discovery Stage Research Projects
Lgr5-mediated self-renewal in B cell selection and leukemia-initiation
$2,183,223
University of California, San Diego
Professor Alysson R Muotri
Quest – Discovery Stage Research Projects
A treatment for Zika virus infection and neuroprotection efficacy
$1,924,524
Stanford University
Dr. Matthew H Porteus
Quest – Discovery Stage Research Projects
Genome Editing to Correct Cystic Fibrosis Mutations in Airway Stem Cells
$1,968,456
University of California, San Francisco
Dr. Julie B Sneddon
Quest – Discovery Stage Research Projects
Designing a cellular niche for transplantation of human embryonic stem cell-derived beta cells
$2,006,076
University of California, Los Angeles
Dr. John P Chute
Quest – Discovery Stage Research Projects
Protein tyrosine phosphatase – sigma inhibitors for hematopoietic regeneration
$2,115,735
University of California, San Diego
Dan S Kaufman
Quest – Discovery Stage Research Projects
Targeted off-the-shelf immunotherapy to treat refractory cancers
$1,936,936
Parkinson’s Institute
Dr. Birgitt Schuele
Quest – Discovery Stage Research Projects
CRISPR/dCas9 mutant targeting SNCA promoter for downregulation of alpha-synuclein expression as a novel therapeutic approach for Parkinson’s disease
$1,288,415
Gladstone Institutes, J. David
Dr. Deepak Srivastava
Quest – Discovery Stage Research Projects
Direct Cardiac Reprogramming for Regenerative Medicine
$2,392,157
University of California, Irvine
Leslie M Thompson
Quest – Discovery Stage Research Projects
hNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease
$1,650,263
Stanford University
Dr. Roel Nusse
Quest – Discovery Stage Research Projects
Preclinical development of human hepatocyte progenitor cells for cell therapy
$1,651,211
University of California, San Francisco
Dr. Tejal Ashwin Desai
Quest – Discovery Stage Research Projects
Thin Film Encapsulation Devices for Human Stem Cell derived Insulin Producing Cells
$1,092,063
Stanford University
Dr. Rosa Bacchetta
Quest – Discovery Stage Research Projects
GENE EDITING FOR FOXP3 IN HUMAN HSC
$984,228
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